The Nucleolus
نویسندگان
چکیده
منابع مشابه
The nucleolus.
When cells are observed by phase contrast microscopy, nucleoli are among the most conspicuous structures. The nucleolus was formally described between 1835 and 1839, but it was another century before it was discovered to be associated with a specific chromosomal locus, thus defining it as a cytogenetic entity. Nucleoli were first isolated in the 1950s, from starfish oocytes. Then, in the early ...
متن کاملThe nucleolus
Are they always about? Not necessarily. They come and go, disappearing in mitosis from late prophase until telophase. During this period, some nucleolar antigens, including RNA polymerase I and topoisomerase I, remain associated with tandemly repeated clusters of ribosomal RNA genes on the condensed chromatin — these chromosomal regions are presumptuously known as nucleolar organising regions (...
متن کاملExternalities and the Nucleolus∗
In most economic applications, externalities prevail: the worth of a coalition depends on how the other players are organized. We show that there is a unique natural way of extending the nucleolus from (coalitional) games without externalities to games with externalities. This is in contrast to the Shapley value and the core for which many different extensions have been proposed.
متن کاملThe plurifunctional nucleolus.
The nucleolus of eukaryotic cells was first described in the early 19th century and was discovered in the 1960s to be the seat of ribosome synthesis. Although rRNA transcription, rRNA processing and ribosome assembly have been clearly established as major functions of the nucleolus, recent studies suggest that the nucleolus participates in many other aspects of gene expression as well. Thus, th...
متن کاملThe nucleolus through the years
At present it is clear that nucleoli are multifunctional cell organelles and participate in the cell proliferation, resting state, differentiation, maturation, aging and death. Therefore, they also represent very useful morphological markers of these cell states under physiological, pathological and experimental conditions. One of important nucleolar functions related to the mentioned cell stat...
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ژورنال
عنوان ژورنال: Cold Spring Harbor Perspectives in Biology
سال: 2010
ISSN: 1943-0264
DOI: 10.1101/cshperspect.a000638